Ph.D., University of North Texas, 2001
Synthetic Organic Chemistry
The oxime ether group is beginning to be incorporated into many
pharmaceutical and agricultural compounds. In many cases this group
enhances the bioavailability and effectiveness of the compound.
Unfortunately, this oxime ether group can exist in two geometric
configurations and generally only one configuration is acceptable
in the desired product. This necessitates a cumbersome and
expensive separation process.
Our research concentrates on developing new synthetic pathways to oxime ethers where the geometric configuration (stereochemistry) of the group is controlled so that only one or predominantly one configuration is formed.
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